Mrs. Whiskerson is the cat Rachel owns in "The One With The Ball". Mrs. Whiskerson is a naked (or "inside out" according to Ross) cat that cost Rachel $1000. The cat reminded her of her grandmother's cat who she used to play with as a child, but she soon learned that Mrs. Whiskerson was not the same. She scratched Rachel and hissed at her any time she went near. Rachel became convinced that she was hissing "Rachel!"

Eventually, Rachel decides to sell Mrs. Whiskerson with no luck until Gunther buys it from her for $1500. He tells her that she can visit her any time she wants. What happens to Mrs. Whiskerson after this point is unknown.